I've used Pihole for years as well as uBlock origin. When I don't have them it's painful. There are no solutions, only tradeoffs. Sometimes I need to disable uBlock. That's easy. Sometimes someone in the house needs to disable pihole. They can switch their DNS on I can temporarily (automatic toggle) Pihole.

I seriously do not know how people use the Internet without DNS filtering and script blocking. The Internet is a cespool of ads and trash. The tradeoff on these tools are worth it to me.

There was a point where I had fiddled with my ublock settings to such an extent that lots of website weren't working.

I love the concept of ad blocking, but then I have to pay a bill or I have my kids do some educational thing (eg Khan Academy) and the adblocker breaks the website and I have to turn it off. I know they have a little toggle for that, but I find that it doesn't work as smoothly as I'd like.

routing through datacenter ip ranges as he suggests has downsides - you'll see a lot more captchas and some websites might outright refuse to serve you because you're not coming from a residential ip

not all ips are created equal

install adguardhome on your router and home server. optionally open ports and use it everywhere

damn bro, you still see ads? do you even know how to use a computer?

ublock origin is your friend.